Propagating Stress Waves During Epithelial Expansion.
نویسندگان
چکیده
Coordinated motion of cell monolayers during epithelial wound healing and tissue morphogenesis involves mechanical stress generation. Here we propose a model for the dynamics of epithelial expansion that couples mechanical deformations in the tissue to contractile activity and polarization in the cells. A new ingredient of our model is a feedback between local strain, polarization, and contractility that naturally yields a mechanism for viscoelasticity and effective inertia in the cell monolayer. Using a combination of analytical and numerical techniques, we demonstrate that our model quantitatively reproduces many experimental findings [Nat. Phys. 8, 628 (2012)], including the buildup of intercellular stresses, and the existence of traveling mechanical waves guiding the oscillatory monolayer expansion.
منابع مشابه
Non -propagating Waves and Behavior of Curtainwall-pile Breakwaters
Abstract Usually, evanescent modes or non-propagating waves are produced when a propagating incident wave impinges on an interface between two media or materials such as curtainwall-pile breakwater (CPB) at a subcritical angle and decay with distance from interface. To achieve an effective prediction of hydrodynamic performance of CPB and overcome the problem of underestimation of energy loss, ...
متن کاملReflection of Waves in a Rotating Transversely Isotropic Thermoelastic Half-space Under Initial Stress
The present paper concerns with the effect of initial stress on the propagation of plane waves in a rotating transversely isotropic medium in the context of thermoelasticity theory of GN theory of type-II and III. After solving the governing equations, three waves propagating in the medium are obtained. The fastest among them is a quasi-longitudinal wave. The slowest of them is a thermal wave. ...
متن کاملSeismic Behavior of 2D Semi-Sine Shaped Hills against Vertically Propagating Incident Waves
This paper presents the preliminary results of an extensive parametric study on seismic response of two-dimensional semi-sine shaped hills to vertically propagating incident P- and SV-waves. Clear perspectives of the induced diffraction and amplification patterns are given by investigation of time-domain and frequency-domain responses. It is shown that site geometry, wave characteristics , and ...
متن کاملPartial-wave expansions of angular spectra of plane waves.
Focused electromagnetic beams are frequently modeled by either an angular spectrum of plane waves or a partial-wave sum of spherical multipole waves. The connection between these two beam models is explored here. The partial-wave expansion of an angular spectrum containing evanescent components is found to possess only odd partial waves. On the other hand, the partial-wave expansion of an alter...
متن کاملComplete Evaluation of Residual Stress States Using Acoustoelasticity Introduction
The acoustoelastic technique for the nondestructive evaluation of stress is based on the stress-induced changes in the speed of wave propagation. In the application of acoustoelasticity. three different approaches have been adopted. For the sake of discussion. we will consider the case of a plane state of stress in an initially isotropic material. The most common technique uses shear waves prop...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Physical review letters
دوره 114 22 شماره
صفحات -
تاریخ انتشار 2015